Hololens（Microsoft Corp.，WA Redmond，WA）是一款头饰，光学透明的增强现实展示，是最近提高医学增强现实研究的主要参与者。在医疗环境中，HoloLens使医生能够立即了解患者信息，直接与他们对临床方案的看法，医学生，可以更好地了解复杂的解剖学或程序，甚至可以通过执行治疗任务。改进，沉浸式指导。在这篇系统的综述中，我们提供了有关医疗领域第一代霍洛伦斯在2016年3月发布到2021年的全面使用的全面概述，一直关注其继任者霍洛伦斯2号。通过系统搜索PubMed和Scopus数据库确定了171个相关出版物。我们分析了这些出版物的预期用例，注册和跟踪的技术方法，数据源，可视化以及验证和评估。我们发现，尽管已经显示出在各种医学场景中使用Hololens的可行性，但在精确，可靠性，可用性，工作流程和感知方面的努力增加了在临床实践中建立AR。

目的：慢性主动脉疾病的监测成像，如解剖，依赖于在预定义主动脉地标随时间获得和比较预定义主动脉标志的横截面直径测量。由于缺乏鲁棒工具，横截面平面的方向由高训练的操作员手动定义。我们展示了如何有效地使用诊所中常规收集的手动注释来缓解该任务，尽管在测量中存在不可忽略的互操作器可变性。影响：通过利用不完美，回顾性的临床注释，可以缓解或自动化且重复的成像任务的弊端。方法论：在这项工作中，我们结合了卷积神经网络和不确定量化方法来预测这种横截面的取向。我们使用11个操作员随机处理的临床数据进行培训，并在3个独立运营商处理的较小集合上进行测试，以评估互通器变异性。结果：我们的分析表明，手动选择的横截面平面的特点是10.6 ^ \ CirC $ 10.6 ^ \ riC $和每角度为21.4美元的协议限额为95％我们的方法显示，静态误差减少3.57秒^ \ rIC $（$ 40.2 $％）和$ 4.11 ^ \ rIC $（$ 32.8 $％），而不是5.4 ^ \ rIC $（$ 49.0 $％）和16.0美元^ \ CIRC $（$ 74.6 $％）对手动处理。结论：这表明预先存在的注释可以是诊所的廉价资源，以便于易于提出和重复的任务，如横截面提取，以便监测主动脉夹层。

深度学习属于人工智能领域，机器执行通常需要某种人类智能的任务。类似于大脑的基本结构，深度学习算法包括一种人工神经网络，其类似于生物脑结构。利用他们的感官模仿人类的学习过程，深入学习网络被送入（感官）数据，如文本，图像，视频或声音。这些网络在不同的任务中优于最先进的方法，因此，整个领域在过去几年中看到了指数增长。这种增长在过去几年中每年超过10,000多种出版物。例如，只有在医疗领域中的所有出版物中覆盖的搜索引擎只能在Q3 2020中覆盖所有出版物的子集，用于搜索术语“深度学习”，其中大约90％来自过去三年。因此，对深度学习领域的完全概述已经不可能在不久的将来获得，并且在不久的将来可能会难以获得难以获得子场的概要。但是，有几个关于深度学习的综述文章，这些文章专注于特定的科学领域或应用程序，例如计算机愿景的深度学习进步或在物体检测等特定任务中进行。随着这些调查作为基础，这一贡献的目的是提供对不同科学学科的深度学习的第一个高级，分类的元调查。根据底层数据来源（图像，语言，医疗，混合）选择了类别（计算机愿景，语言处理，医疗信息和其他工程）。此外，我们还审查了每个子类别的常见架构，方法，专业，利弊，评估，挑战和未来方向。

Machine learning models are typically evaluated by computing similarity with reference annotations and trained by maximizing similarity with such. Especially in the bio-medical domain, annotations are subjective and suffer from low inter- and intra-rater reliability. Since annotations only reflect the annotation entity's interpretation of the real world, this can lead to sub-optimal predictions even though the model achieves high similarity scores. Here, the theoretical concept of Peak Ground Truth (PGT) is introduced. PGT marks the point beyond which an increase in similarity with the reference annotation stops translating to better Real World Model Performance (RWMP). Additionally, a quantitative technique to approximate PGT by computing inter- and intra-rater reliability is proposed. Finally, three categories of PGT-aware strategies to evaluate and improve model performance are reviewed.

Achieving artificially intelligent-native wireless networks is necessary for the operation of future 6G applications such as the metaverse. Nonetheless, current communication schemes are, at heart, a mere reconstruction process that lacks reasoning. One key solution that enables evolving wireless communication to a human-like conversation is semantic communications. In this paper, a novel machine reasoning framework is proposed to pre-process and disentangle source data so as to make it semantic-ready. In particular, a novel contrastive learning framework is proposed, whereby instance and cluster discrimination are performed on the data. These two tasks enable increasing the cohesiveness between data points mapping to semantically similar content elements and disentangling data points of semantically different content elements. Subsequently, the semantic deep clusters formed are ranked according to their level of confidence. Deep semantic clusters of highest confidence are considered learnable, semantic-rich data, i.e., data that can be used to build a language in a semantic communications system. The least confident ones are considered, random, semantic-poor, and memorizable data that must be transmitted classically. Our simulation results showcase the superiority of our contrastive learning approach in terms of semantic impact and minimalism. In fact, the length of the semantic representation achieved is minimized by 57.22% compared to vanilla semantic communication systems, thus achieving minimalist semantic representations.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Both clustering and outlier detection play an important role for meteorological measurements. We present the AWT algorithm, a clustering algorithm for time series data that also performs implicit outlier detection during the clustering. AWT integrates ideas of several well-known K-Means clustering algorithms. It chooses the number of clusters automatically based on a user-defined threshold parameter, and it can be used for heterogeneous meteorological input data as well as for data sets that exceed the available memory size. We apply AWT to crowd sourced 2-m temperature data with an hourly resolution from the city of Vienna to detect outliers and to investigate if the final clusters show general similarities and similarities with urban land-use characteristics. It is shown that both the outlier detection and the implicit mapping to land-use characteristic is possible with AWT which opens new possible fields of application, specifically in the rapidly evolving field of urban climate and urban weather.

Deep learning classifiers provide the most accurate means of automatically diagnosing diabetic retinopathy (DR) based on optical coherence tomography (OCT) and its angiography (OCTA). The power of these models is attributable in part to the inclusion of hidden layers that provide the complexity required to achieve a desired task. However, hidden layers also render algorithm outputs difficult to interpret. Here we introduce a novel biomarker activation map (BAM) framework based on generative adversarial learning that allows clinicians to verify and understand classifiers decision-making. A data set including 456 macular scans were graded as non-referable or referable DR based on current clinical standards. A DR classifier that was used to evaluate our BAM was first trained based on this data set. The BAM generation framework was designed by combing two U-shaped generators to provide meaningful interpretability to this classifier. The main generator was trained to take referable scans as input and produce an output that would be classified by the classifier as non-referable. The BAM is then constructed as the difference image between the output and input of the main generator. To ensure that the BAM only highlights classifier-utilized biomarkers an assistant generator was trained to do the opposite, producing scans that would be classified as referable by the classifier from non-referable scans. The generated BAMs highlighted known pathologic features including nonperfusion area and retinal fluid. A fully interpretable classifier based on these highlights could help clinicians better utilize and verify automated DR diagnosis.

Text generation has long been a popular research topic in NLP. However, the task of generating recruitment emails from recruiters to candidates in the job recommendation scenario has received little attention by the research community. This work aims at defining the topic of automatic email generation for job recommendation, identifying the challenges, and providing a baseline template-based solution for Danish jobs. Evaluation by human experts shows that our method is effective. We wrap up by discussing the future research directions for better solving this task.

Because noise can interfere with downstream analysis, image denoising has come to occupy an important place in the image processing toolbox. The most accurate state-of-the-art denoisers typically train on a representative dataset. But gathering a training set is not always feasible, so interest has grown in blind zero-shot denoisers that train only on the image they are denoising. The most accurate blind-zero shot methods are blind-spot networks, which mask pixels and attempt to infer them from their surroundings. Other methods exist where all neurons participate in forward inference, however they are not as accurate and are susceptible to overfitting. Here we present a hybrid approach. We first introduce a semi blind-spot network where the network can see only a small percentage of inputs during gradient update. We then resolve overfitting by introducing a validation scheme where we split pixels into two groups and fill in pixel gaps using domino tilings. Our method achieves an average PSNR increase of $0.28$ and a three fold increase in speed over the current gold standard blind zero-shot denoiser Self2Self on synthetic Gaussian noise. We demonstrate the broader applicability of Pixel Domino Tiling by inserting it into a preciously published method.